Scientists Have Observed Epigenetic Memories Being Passed Down for 14 Generations

The most important set of genetic instructions we all get comes from our DNA, passed down through generations. But the environment we live in can make genetic changes, too.
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Researchers have now discovered that these kinds of environmental genetic changes can be passed down for a whopping 14 generations in an animal – the largest span ever observed in a creature, in this case being a dynasty of C. elegans nematodes (roundworms). Read more

Two Drugs Identified That Could Halt The Progression Of Neurodegenerative Diseases

Researchers have found two drugs already in various stages of use and human clinical trial that seem to prevent all neurodegenerative diseases in mice

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A Warp In Space-Time Just Gave Us Four Views Of One Exploding Star

Like a lens, a galaxy (center, blue) passing in front of a supernova has split its light into four images (yellow/orange), and magnified its intensity by 52 times.
Like a lens, a galaxy (center, blue) passing in front of a supernova has split its light into four images (yellow/orange), and magnified its intensity by 52 times.

Although the night sky often seems so peaceful and still, a closer look reveals constant movement and change. The Intermediate Palomar Transient Factory (iPTF) in California looks for ephemeral phenomena in the heavens, like stars that fluctuate in brightness, or planets passing in front of their stars.

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One night in September of 2016, the observatory spotted something that hadn’t been there before: a supernova had popped onto the scene.

“What caught my immediate attention on this one is that it was way too bright, considering its distance to us,” says Ariel Goobar, a cosmology and physics researcher at Stockholm University. “It shone more than 50 times more intensely than it should.”

Once he and his colleagues were sure there was nothing wrong with their data, they realized that the light from the supernova was getting magnified by a galaxy passing in front of it. Zooming in, they realized they could actually see four different images of the supernova surrounding the intervening galaxy.

The results are published today in Science, and they could help measure how quickly the universe is expanding—something cosmologists are still debating. Read more

ALMA (ESO/NRAO/NAOJ), L. Calçada (ESO), Y. Hezaveh et al., edited and modified by Joel Johansson Bent by the galaxy's gravity, light from the supernova took four different paths to get to Earth. Estimating how long it took for the images to reach Earth could help to pinpoint how quickly the universe is expanding.
ALMA (ESO/NRAO/NAOJ), L. Calçada (ESO), Y. Hezaveh et al., edited and modified by Joel Johansson
Bent by the galaxy’s gravity, light from the supernova took four different paths to get to Earth. Estimating how long it took for the images to reach Earth could help to pinpoint how quickly the universe is expanding.

Old Mice Made Young Again With New Anti-Aging Drug

Old Mice Made Young Again With New Anti-Aging Drug

There’s something eerily dystopian about the lives of cells.

Like the young heroes in popular teen novels, cells are born into stringent organ “societies,” destined to perform specific roles preordained by their DNA expression. Like the bodies they inhabit, cells have limited lifespans, and when they grow old, they begin leaking toxic molecules into their surroundings.

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But sometimes aged cells go rogue. Rather than committing suicide, these cells lurk in our hearts, livers, kidneys and brains, where they silently promote disease. Scientists have long suspected that these “senescent” cells cause us to age, but getting rid of them without harming normal, healthy cells has been challenging.

Now, a collaborative effort between the Erasmus University in the Netherlands and the Buck Institute for Research on Aging in California may have a solution. Published in the prestigious journal Cell, the team developed a chemical torpedo that, after injecting into mice, zooms to senescent cells and puts them out of their misery, while leaving healthy cells alone. Read more